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Article

CD4 T-cells regulate angiogenesis and myogenesis.

Biomaterials - 1 Sept 2018

Kwee Brian J, Budina Erica, Najibi Alexander J, Mooney David J

Abstract excerpt

Ischemic diseases, such as peripheral artery disease, affect millions of people worldwide. While CD4+ T-cells regulate angiogenesis and myogenesis, it is not understood how the phenotype of these adaptive immune cells regulate these regenerative processes. The secreted factors from different types of CD4+ T-cells (Th1, Th2, Th17, and Treg) were utilized in a series of in vitro assays and delivered from an...

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Identifiers

PMID: 29920403
DOI: 10.1016/j.biomaterials.2018.06.003
PMCID: PMC6090550

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