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Isothermal amplification using modified primers for rapid electrochemical analysis of coeliac disease associated DQB1*02 HLA allele.

Analytical biochemistry - 1 Sept 2018

Al-Madhagi Sallam, Joda Hamdi, Jauset-Rubio Miriam, Ortiz Mayreli, Katakis Ioanis, O'Sullivan Ciara K

Abstract excerpt

DNA biosensors are attractive tools for genetic analysis as there is an increasing need for rapid and low-cost DNA analysis, primarily driven by applications in personalized pharmacogenomics, clinical diagnostics, rapid pathogen detection, food traceability and forensics. A rapid electrochemical genosensor detection methodology exploiting a combination of modified primers for solution-phase isothermal...

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PMID: 29920236
DOI: 10.1016/j.ab.2018.06.013

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