Article
Update on the genetics of nonbacterial osteomyelitis in humans.
Current opinion in rheumatology - 1 Sept 2018
Cox Allison J, Ferguson Polly J
Abstract excerpt
PURPOSE OF REVIEW: To summarize the current advances in our understanding or the genetic basis of nonbacterial osteomyelitis. RECENT FINDINGS: Chronic recurrent multifocal osteomyelitis (CRMO) is a complex genetic disorder. Past discoveries identified several single gene defects (LPIN2, Pstpip2 and IL1RN) that cause IL-1-mediated sterile multifocal osteomyelitis. Recently Lorden et al.'s studies show that LIPIN2...
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