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Molecular profiles and tumor mutational burden analysis in Chinese patients with gynecologic cancers.

Scientific reports - 12 Jun 2018

Wang Min, Fan Wensheng, Ye Mingxia, Tian Chen, Zhao Lili, Wang Jianfei, Han Wenbo, Yang Wen, Gu Chenglei, Li Mingxia, Zhang Zhe, Wang Yongjun, Zhang Henghui, Meng Yuanguang

Abstract excerpt

The goal of this work was to investigate the tumor mutational burden (TMB) in Chinese patients with gynecologic cancer. In total, 117 patients with gynecologic cancers were included in this study. Both tumor DNA and paired blood cell genomic DNA were isolated from formalin-fixed paraffin-embedded (FFPE) specimens and blood samples, and next-generation sequencing was performed to identify somatic mutations. TP53,...

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Identifiers

PMID: 29895933
DOI: 10.1038/s41598-018-25583-6
PMCID: PMC5997642

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PTEN
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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