Article
The clinical significance of platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) in gastric cancer: A systematic review and meta-analysis.
Critical reviews in oncology/hematology - 1 Jul 2018
Qian Hai, Appiah-Kubi Kwaku, Wang Ying, Wu Min, Tao Yan, Wu Yan, Chen Yongchang
Abstract excerpt
BACKGROUND: The overexpression and mutation of platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) are widespread in cancers and have been recognized as attractive oncologic targets with diverse therapeutic targets. Reports of the overexpression of genes, proteins and mutations of PDGFs/PDGFRs in gastric cancer and their associations with clinicopathological features, Western and Asian patients,...
Topics
- Biomarkers, Tumor
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Male
- Mutation
- Neoplasm Recurrence, Local
- Platelet-Derived Growth Factor
- Prognosis
- Receptors, Platelet-Derived Growth Factor
- Stomach Neoplasms