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Article

Sex-Specific Epigenetic Mediators Between Early Life Social Disadvantage and Adulthood BMI

1 Jun 2018

Abstract excerpt

AIM: The objective of this study was to identify potential epigenetic mediating pathways linking early life social disadvantage (ELSD) to adulthood BMI. METHODS: Sex-specific epigenome-wide two-stage mediation analyses were conducted in blood and adipose tissue, and mediation estimates were obtained using cross-product mediation analysis. Pathway analyses were conducted using GREAT software (Bejerano Lab, CA,...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 29888956
DOI: 10.2217/epi-2017-0146

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