Article
Mutations in blind cavefish target the light-regulated circadian clock gene, period 2.
Scientific reports - 8 Jun 2018
Ceinos Rosa Maria, Frigato Elena, Pagano Cristina, Fröhlich Nadine, Negrini Pietro, Cavallari Nicola, Vallone Daniela, Fuselli Silvia, Bertolucci Cristiano, Foulkes Nicholas S
Abstract excerpt
Light represents the principal signal driving circadian clock entrainment. However, how light influences the evolution of the clock remains poorly understood. The cavefish Phreatichthys andruzzii represents a fascinating model to explore how evolution under extreme aphotic conditions shapes the circadian clock, since in this species the clock is unresponsive to light. We have previously demonstrated that...
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