Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

COMT and the neurogenetic architecture of hearing loss induced tinnitus.

Hearing research - 1 Aug 2018

Vanneste Sven, Alsalman Ola, De Ridder Dirk

Abstract excerpt

As the COMT polymorphism is especially prominent in the prefrontal cortex and has been associated with auditory gating, we hypothesize that tinnitus patients with this polymorphism have altered activity in the ventromedial prefrontal/anterior cingulate areas that modulates the tinnitus percept. To test this, we recruited a total of 40 tinnitus subjects and 20 healthy controls for an EEG study. A comparison...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Auditory Perception
Share to Brain
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Hearing

Share to Hearing Loss

Share to Severity of Illness Index

Share to Tinnitus

Source

Identifiers

PMID: 29883832
DOI: 10.1016/j.heares.2018.05.020

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

COMT and the neurogenetic architecture of hearing loss induced tinnitus.PMID 29883832Read ↗

A genome-wide association study of tinnitus reveals shared genetic links to neuropsychiatric disorders.Semantic proximity Read ↗

Causal Associations of Genetically Determined Tinnitus With Neuroimaging Traits: Evidence From a Mendelian Randomization Study.Semantic proximity Read ↗

Mendelian randomization analyses support causal relationships between tinnitus of different stages and severity and structural characteristics of specific brain regions.Semantic proximity Read ↗

Genetics of chronic tinnitus.Semantic proximity Read ↗

Cluster analysis for identifying sub-types of tinnitus: a positron emission tomography and voxel-based morphometry study.Semantic proximity Read ↗

Heritability and Genetics Contribution to Tinnitus.Semantic proximity Read ↗

Novel Risk Loci in Tinnitus and Causal Inference With Neuropsychiatric Disorders Among Adults of European Ancestry.Semantic proximity Read ↗

Aberrant Functional and Effective Connectivity of the Frontostriatal Network in Unilateral Acute Tinnitus Patients with Hearing LossSemantic proximity Read ↗

Increased basal ganglia volume in older adults with tinnitusSemantic proximity Read ↗

COMT Val108/158Met genotype modulates human sensory gating.Semantic proximity Read ↗

Tinnitus: Prevalence, Risk Factors, and Associations with Psychological Health and Auditory SafetySemantic proximity Read ↗

Prevalence of misophonia in the general population and those with complaints of tinnitus: An epidemiological studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.