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Article

A novel mutation in the proopiomelanocortin (POMC) gene of a Hispanic child: metformin treatment shows a beneficial impact on the body mass index.

Journal of pediatric endocrinology & metabolism : JPEM - 26 Jul 2018

Hilado Mark A, Randhawa Ruvdeep S

Abstract excerpt

Background Proopiomelanocortin (POMC) is a complex polypeptide that produces a variety of biologically active substances via cleavage in a tissue-specific manner [Challis BG, Millington GW. Proopiomelanocortin deficiency. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle, 1993-2018], yielding several products including adrenocorticotrophic (ACTH) and melanocyte stimulating hormones (MSH)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29858905
DOI: 10.1515/jpem-2017-0467

Genes

POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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A novel mutation in the proopiomelanocortin (POMC) gene of a Hispanic child: metformin treatment shows a beneficial impact on the body mass index.PMID 29858905Read ↗

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Implications of proopiomelanocortin (POMC) mutations in humans: the POMC deficiency syndrome.Semantic proximity Read ↗

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