Article
Association of branched chain amino acids related variant rs1440581 with risk of incident diabetes and longitudinal changes in insulin resistance in Chinese.
Acta diabetologica - 1 Sept 2018
Xuan Liping, Hou Yanan, Wang Tiange, Li Mian, Zhao Zhiyun, Lu Jieli, Xu Yu, Chen Yuhong, Qi Lu, Wang Weiqing, Bi Yufang, Xu Min
Abstract excerpt
AIMS: Previous genome-wide association studies reported rs1440581 was significantly associated with circulating branched chain amino acids (BCAAs) levels in Europeans. We aimed to investigate association of BCAAs related variant rs1440581 with incident T2D risk and longitudinal changes in glucose-related metabolic traits in a community-based prospective cohort of Chinese. METHODS: 6043 non-diabetic participants...
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