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Article

A single nucleotide polymorphism in BCAT1 gene is associated with type 2 diabetes mellitus.

Acta biochimica Polonica - 21 Dec 2021

Alfaqih Mahmoud A, Abu-Khdair Zaina E, Khabour Omar, Kheirallah Khalid A, Khanfar Mariam

Abstract excerpt

The level of circulatory branched chain amino acids (BCAAs) is often increased in type 2 diabetes mellitus (T2DM). Catabolism of BCAAs involves a transamination reaction mediated by the branched chain amino acid aminotransferase (BCAT1) enzyme. Differences in the level of BCAT1 were found to be linked with hypertension, obesity, and cancer. Herein, using a case control design, we tested the association of...

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Identifiers

PMID: 34932898
DOI: 10.18388/abp.2018_5481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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