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Inhibitory effects of Myricetin derivatives on curli-dependent biofilm formation in Escherichia coli

25 May 2018

Abstract excerpt

Abstract Biofilms are well-organised communities of microbes embedded in a self-produced extracellular matrix (e.g., curli amyloid fibers) and are associated with chronic infections. Therefore, development of anti-biofilm drugs is important to combat with these infections. Previously, we found that flavonol Myricetin inhibits curli-dependent biofilm formation by Escherichia coli (IC50 = 46.2 μM). In this study,...

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PMID: 29855532
DOI: 10.1038/s41598-018-26748-z

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