Article
Secretion of curli fibre subunits is mediated by the outer membrane-localized CsgG protein.
Molecular microbiology - 1 Feb 2006
Robinson Lloyd S, Ashman Elisabeth M, Hultgren Scott J, Chapman Matthew R
Abstract excerpt
Produced by many Enterobacteriaceae spp., curli are biologically important amyloid fibres that have been associated with biofilm formation, host cell adhesion and invasion, and immune system activation. CsgA is the major fibre subunit and CsgE, CsgF and CsgG are non-structural proteins involved in curli biogenesis. We have characterized the role of CsgG in curli subunit secretion across the outer membrane....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
