Article
Role of Helicobacter pylori CagA + Infection in Determining Oxidative DNA Damage in Gastric Mucosa
1 Jan 2002
Abstract excerpt
BACKGROUND: Although Helicobacter pylori is a risk factor for gastric cancer, the role of the bacterium in the development of this malignancy is not defined precisely. Reactive oxygen species (ROS) could play an important role in carcinogenesis by inducing DNA damage. The aims of the present study were: 1) to assess the production of ROS and 8-hydroxy-2'-deoxyguanosine (8-OHdG), a sensitive marker of oxidative...
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