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Gene co-expression network analysis for identifying genetic markers in Parkinson's disease - a three-way comparative approach

28 May 2018

Abstract excerpt

Parkinson's disease (PD) is a neurodegenerative disorder involving progressive deterioration of dopaminergic neurons. Although few genetic markers for familial PD are known, the etiology of sporadic PD remains poorly understood. Microarray data was analysed for induced pluripotent stem cells (iPSCs) derived from PD patients and mature neuronal cells (mDA) differentiated from these iPSCs. Combining expression and...

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PMID: 29852216
DOI: 10.1016/j.ygeno.2018.05.005

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