Article
Association of the polymorphisms in Th2 chemotaxis-related genes with the development and prognosis of autoimmune thyroid diseases.
Endocrine journal - 27 Aug 2018
Omori Naoki, Watanabe Mikio, Inoue Naoya, Taniguchi Junpei, Hidaka Yoh, Iwatani Yoshinori
Abstract excerpt
The prognosis of autoimmune thyroid disease (AITD) is difficult to predict. Th2 cells suppress the differentiation of Th1 and Th17 cells, which are associated with the prognosis of AITD. However, there are few reports as to whether Th2 chemotaxis-related genes, such as CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), IL-25, TARC/CCL17 (Thymus and activation regulated...
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