Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Initiation and maintenance of latent herpes simplex virus infections: the paradox of perpetual immobility and continuous movement.

Reviews of infectious diseases - 1 Jan 2000

Klein R J

Abstract excerpt

During the acute phase of infection, herpes simplex virus (HSV) is taken up by nerve endings and travels, probably as a noninfectious nucleocapsid, toward the neurons of sensory ganglia. Infectious virus can be detected in ganglia for a limited period, after which the virus enters into a latent phase. It appears that synthesis of deoxyribonucleic acid is not required and that an early viral protein and at least...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpes Simplex
Share to Movement
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nervous System

Share to Recurrence

Share to Simplexvirus

Share to Virus Activation

Share to Virus Replication

Source

Identifiers

PMID: 2984757
DOI: 10.1093/clinids/7.1.21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Initiation and maintenance of latent herpes simplex virus infections: the paradox of perpetual immobility and continuous movement.PMID 2984757Read ↗

Herpes Simplex Virus Establishment, Maintenance, and Reactivation: In Vitro Modeling of LatencySemantic proximity Read ↗

Lytic Gene Expression Is Frequent in HSV-1 Latent Infection and Correlates with the Engagement of a Cell-Intrinsic Transcriptional ResponseSemantic proximity Read ↗

The molecular basis of herpes simplex virus latencySemantic proximity Read ↗

An Immortalized Human Dorsal Root Ganglion Cell Line Provides a Novel Context To Study Herpes Simplex Virus 1 Latency and ReactivationSemantic proximity Read ↗

Restarting Lytic Gene Transcription at the Onset of Herpes Simplex Virus ReactivationSemantic proximity Read ↗

Role of herpes simplex virus thymidine kinase expression in viral pathogenesis and latency.Semantic proximity Read ↗

The herpes simplex virus type 1 latency associated transcript locus is required for the maintenance of reactivation competent latent infections.Semantic proximity Read ↗

Modeling HSV-1 Latency in Human Embryonic Stem Cell-Derived NeuronsSemantic proximity Read ↗

A historical analysis of herpes simplex virus promoter activation in vivo reveals distinct populations of latently infected neuronesSemantic proximity Read ↗

Ocular Herpes Simplex Virus: How are Latency, Reactivation, Recurrent Disease and Therapy Interrelated?Semantic proximity Read ↗

DLK-dependent biphasic reactivation of herpes simplex virus latency established in the absence of antiviralsSemantic proximity Read ↗

Herpes Simplex Virus Latency Is Noisier the Closer We LookSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.