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Article

Initiation and maintenance of latent herpes simplex virus infections: the paradox of perpetual immobility and continuous movement.

Reviews of infectious diseases - 1 Jan 2000

Klein R J

Abstract excerpt

During the acute phase of infection, herpes simplex virus (HSV) is taken up by nerve endings and travels, probably as a noninfectious nucleocapsid, toward the neurons of sensory ganglia. Infectious virus can be detected in ganglia for a limited period, after which the virus enters into a latent phase. It appears that synthesis of deoxyribonucleic acid is not required and that an early viral protein and at least...

Topics

Animals
Herpes Simplex
Humans
Movement
Mutation
Nervous System
Recurrence
Simplexvirus
Virus Activation
Virus Replication

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2984757
DOI: 10.1093/clinids/7.1.21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2984757-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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