Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SOX2 Targets Fibronectin 1 to Promote Cell Migration and Invasion in Ovarian Cancer: New Molecular Leads for Therapeutic Intervention

29 Jul 2013

Abstract excerpt

Abstract Ovarian cancer ranks as the second most common tumor of the female reproductive system, with a large burden on global public health. Therefore, the identification of novel molecular targets and diagnostics is an urgent need for many women affected by this disease. To this end, the human transcription factor SOX2 is involved in a wide range of pathophysiological roles, such as the maintenance of stem cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to MicroRNA in disease regulation
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23895273
DOI: 10.1089/omi.2013.0058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SOX2 Targets Fibronectin 1 to Promote Cell Migration and Invasion in Ovarian Cancer: New Molecular Leads for Therapeutic InterventionPMID 23895273Read ↗

Enhanced ZNF521 expression induces an aggressive phenotype in human ovarian carcinoma cell lines.Semantic proximity Read ↗

SOX2 Promotes Brain Metastasis of Breast Cancer by Upregulating the Expression of FSCN1 and HBEGFSemantic proximity Read ↗

Sox2 is required for tumor development and cancer cell proliferation in osteosarcomaSemantic proximity Read ↗

Characterization of SOX2, OCT4 and NANOG in Ovarian Cancer Tumor-Initiating CellsSemantic proximity Read ↗

Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies.Semantic proximity Read ↗

SIX2 Mediates Late-Stage Metastasis via Direct Regulation of SOX2 and Induction of a Cancer Stem Cell ProgramSemantic proximity Read ↗

Clinical Correlation of Transcription Factor SOX3 in Cancer: Unveiling Its Role in TumorigenesisSemantic proximity Read ↗

<scp>SOX</scp>2 is required to maintain cancer stem cells in ovarian cancerSemantic proximity Read ↗

UnPAXing the Divergent Roles of PAX2 and PAX8 in High-Grade Serous Ovarian CancerSemantic proximity Read ↗

SOX8 acts as a prognostic factor and mediator to regulate the progression of triple-negative breast cancerSemantic proximity Read ↗

Silencing SOX2 Induced Mesenchymal-Epithelial Transition and Its Expression Predicts Liver and Lymph Node Metastasis of CRC PatientsSemantic proximity Read ↗

LncRNA SOX2‐OT is a novel prognostic biomarker for osteosarcoma patients and regulates osteosarcoma cells proliferation and motility through modulating SOX2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.