Article
The impact of growth rate and environmental factors on mutation rates and spectra in Escherichia coli.
Environmental microbiology reports - 1 Dec 2018
Maharjan Ram P, Ferenci Thomas
Abstract excerpt
Genetic variation in bacterial populations is remarkably sensitive to environmental influences, including simple, nutritional differences. Not only the rate but also the kind of mutational changes is biased by the nutritional state of bacteria. Here we investigate the mutational consequences of a universal variable for free-living bacteria, namely the growth rate. By controlling growth in chemostats, the rate and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
