Quantitative Proteome Analysis of <i>Streptomyces coelicolor</i> Nonsporulating Liquid Cultures Demonstrates a Complex Differentiation Process Comparable to That Occurring in Sporulating Solid Cultures

Abstract excerpt

Streptomyces species produce many clinically important secondary metabolites and present a complex developmental cycle that includes programmed cell death (PCD) phenomena and sporulation. Industrial fermentations are usually performed in liquid cultures, conditions in which Streptomyces strains generally do not sporulate, and it was traditionally assumed that no differentiation took place. Recently, the existence...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Fungal Biology and Applications
• Share to Microbial Natural Products and Biosynthesis