Article
Potential Role of Gut Microbiota in ALS Pathogenesis and Possible Novel Therapeutic Strategies.
Journal of clinical gastroenterology - 1 Jan 2000
Mazzini Letizia, Mogna Luca, De Marchi Fabiola, Amoruso Angela, Pane Marco, Aloisio Irene, Cionci Nicole Bozzi, Gaggìa Francesca, Lucenti Ausiliatrice, Bersano Enrica, Cantello Roberto, Di Gioia Diana, Mogna Giovanni
Abstract excerpt
BACKGROUND: Recent preclinical studies suggest that dysfunction of gastrointestinal tract may play a role in amyotrophic lateral sclerosis (ALS) pathogenesis through a modification of the gut microbiota brain axis. Our study is the first focused on microbiota analysis in ALS patients. AIM: Our aim was to study the main human gut microbial groups and the overall microbial diversity in ALS and healthy subjects....
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