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Article

Physiological and Molecular Mechanisms of Methionine Restriction

4 May 2018

Abstract excerpt

Methionine restriction (MR) has been studied extensively over the last 25 years for its role in altering metabolic hallmarks of disease. Animals subjected to MR, display changes in metabolic flexibility demonstrated by increases in energy expenditure, glucose tolerance, and lifespan. These changes have been well characterized in a number of model systems and significant progress has been made in understanding how...

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PMID: 29780356
DOI: 10.3389/fendo.2018.00217

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