Article
Characterization of the genetic diversity of extensively-drug resistant Mycobacterium tuberculosis clinical isolates from pulmonary tuberculosis patients in Peru.
PloS one - 1 Jan 2014
Cáceres Omar, Rastogi Nalin, Bartra Carlos, Couvin David, Galarza Marco, Asencios Luis, Mendoza-Ticona Alberto
Abstract excerpt
BACKGROUND: Peru holds the fourth highest burden of tuberculosis in the Americas. Despite an apparently well-functioning DOTS control program, the prevalence of multidrug resistant tuberculosis (MDR-TB) continues to increase. To worsen this situation, cases of extensively drug resistance tuberculosis (XDR-TB) have been detected. Little information exists about the genetic diversity of drug-susceptible vs. MDR-TB...
Topics
- Adult
- Antitubercular Agents
- Evolution, Molecular
- Extensively Drug-Resistant Tuberculosis
- Female
- Genetic Loci
- Genetic Variation
- Genotyping Techniques
- Humans
- Injections