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Article

Novel internal regulators and candidate miRNAs within miR-379/miR-656 miRNA cluster can alter cellular phenotype of human glioblastoma.

Scientific reports - 16 May 2018

Nayak Subhashree, Aich Meghali, Kumar Anupam, Sengupta Suman, Bajad Prajakta, Dhapola Parashar, Paul Deepanjan, Narta Kiran, Purkrait Suvendu, Mehani Bharati, Suri Ashish, Chakraborty Debojyoti, Mukhopadhyay Arijit, Sarkar Chitra

Abstract excerpt

Clustered miRNAs can affect functioning of downstream pathways due to possible coordinated function. We observed 78-88% of the miR-379/miR-656 cluster (C14MC) miRNAs were downregulated in three sub-types of diffuse gliomas, which was also corroborated with analysis from The Cancer Genome Atlas (TCGA) datasets. The miRNA expression levels decreased with increasing tumor grade, indicating this downregulation as an...

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Identifiers

PMID: 29769662
DOI: 10.1038/s41598-018-26000-8
PMCID: PMC5955984

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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