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Article

NextGen nuclear DNA sequencing in cyclic vomiting syndrome reveals a significant association with the stress-induced calcium channel (RYR2).

Neurogastroenterology and motility - 1 Jul 2015

Lee J, Wong S A, Li B U K, Boles R G

Abstract excerpt

BACKGROUND: Cyclic vomiting syndrome (CVS) is a common, frequently disabling, 'functional' condition characterized by recurring, stereotypical attacks of intense nausea, vomiting, and lethargy, with the essential absence of these symptoms between episodes. Although the pathogenesis of CVS is yet unexplained, evidence has accumulated which suggest pathogenic roles for stress-related, autonomic, neuroendocrine, and...

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Identifiers

PMID: 25925909
DOI: 10.1111/nmo.12575

Genes

RYR2

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