Article
Taurine Protects from Pentylenetetrazole-Induced Behavioral and Neurochemical Changes in Zebrafish.
Molecular neurobiology - 1 Jan 2019
Fontana Barbara D, Ziani Paola R, Canzian Julia, Mezzomo Nathana J, Müller Talise E, Dos Santos Matheus M, Loro Vania L, Barbosa Nilda V, Mello Carlos F, Rosemberg Denis B
Abstract excerpt
Epilepsy is a common neurological disorder characterized by recurrent unprovoked seizures, which culminate in various neurobehavioral and neurochemical changes. Taurine (TAU) is an amino sulfonic acid which acts an endogenous inhibitory neuromodulator. Moreover, TAU displays intrinsic antioxidant activity, contributing to its beneficial actions in the CNS. Here, we evaluated whether TAU pretreatment protects from...
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