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Genetic variants in SLC7A7 are associated with risk of glioma in a Chinese population.

Experimental biology and medicine (Maywood, N.J.) - 1 Sept 2013

Fan Songhua, Zhao Yingjie, Li Xiaoying, Du Yanli, Wang Jingkun, Song Xiao, Zhou Fangfang, Chen Hongyan, Chen Gong, Zhao Yao, Mao Ying, Lan Qing

Abstract excerpt

Dysregulation of the amino acid transporter SLC7A7 is involved in multiple types of cancer including gliobastoma (GBM), the most malignant form of glioma. We hypothesized that SLC7A7 genetic variants may influence glioma risk. To test this hypothesis, we conducted a case-control study in 736 incident glioma cases and 793 cancer-free controls in a Chinese population by genotyping 22 common single nucleotide...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Amino Acid Transport System y+L
Brain Neoplasms
Female
Fusion Regulatory Protein 1, Light Chains
Gene Frequency
Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Genotype

Glioma

Humans

Male

Middle Aged

Multivariate Analysis

Odds Ratio

Source

Identifiers

PMID: 23975734
DOI: 10.1177/1535370213498977

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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