Molecular insight and pharmacological approaches targeting mitochondrial dynamics in skeletal muscle during obesity

Abstract excerpt

Obesity-associated insulin resistance is the major characteristic of the early stage of metabolic syndrome. A decline in mitochondrial function plays a role in the development of insulin resistance in obesity and type 2 diabetes. Accumulating data reveal that mitochondrial dynamics, the balance between mitochondrial fusion and fission, are an important factor in the maintenance of mitochondrial function. Thus,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adipose Tissue and Metabolism
• Share to ATP Synthase and ATPases Research
• Share to Mitochondrial Function and Pathology