Article
Porcine IGF1 synonymous mutation alter gene expression and protein binding affinity with IGF1R.
International journal of biological macromolecules - 1 Sept 2018
Cheng Yunyun, Liu Songcai, Wang Gang, Wei Wenzhen, Huang Shan, Yang Rui, Geng Hongwei, Li Haoyang, Song Jie, Sun Lidan, Yu Hao, Hao Linlin
Abstract excerpt
CONTEXT: Insulin like growth factor 1 (IGF1) is privotal in the regulation of animal growth and is a single-chain globular protein composed of B, C, A, and D regions, of which the C region is involved in maintaining high affinity binding to the IGF1 receptor (IGF1R). PURPOSE: In this study, significant expression differences between large pigs and miniature pigs were detected and only one synonymous SNP...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.