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Cloning, chromosomal localization, SNP detection and association analysis of the porcine IRS-1 gene.

Molecular biology reports - 1 Nov 2009

Niu P-X, Huang Z, Li C-C, Fan B, Li K, Liu B, Yu M, Zhao S-H

Abstract excerpt

Insulin receptor substrate-1(IRS-1) gene is one member of the Insulin receptor substrate (IRS) gene family, which plays an important role in mediating the growth of skeletal muscle and the molecular metabolism of type 2 diabetes. Here, we cloned a 3,573 bp fragment of the partial CDS sequence of porcine IRS-1 gene by in silicon cloning strategy and RT-PCR method. The porcine IRS-1 gene was assigned to SSC15q25 by...

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PMID: 19093226
DOI: 10.1007/s11033-008-9420-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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