Article
A coupled process of same- and opposite-sex mating generates polyploidy and genetic diversity in Candida tropicalis.
PLoS genetics - 1 May 2018
Du Han, Zheng Qiushi, Bing Jian, Bennett Richard J, Huang Guanghua
Abstract excerpt
Sexual reproduction is a universal mechanism for generating genetic diversity in eukaryotes. Fungi exhibit diverse strategies for sexual reproduction both in nature and in the laboratory. In this study, we report the discovery of same-sex (homothallic) mating in the human fungal pathogen Candida tropicalis. We show that same-sex mating occurs between two cells carrying the same mating type (MTLa/a or α/α) and...
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