Article
From glycophenotyping by (plant) lectin histochemistry to defining functionality of glycans by pairing with endogenous lectins.
Histochemistry and cell biology - 1 Jun 2018
Kaltner Herbert, García Caballero Gabriel, Ludwig Anna-Kristin, Manning Joachim C, Gabius Hans-Joachim
Abstract excerpt
About 60 years ago, the efforts to identify blood group-specific haemagglutinins in plant extracts by broad-scale testing were beginning to make a large panel of these proteins available as laboratory tools. Their ability to 'read' cell surface signals like antibodies do was the reason for W. C. Boyd to call them lectins, from Latin legere (to read). These proteins turned out to be as widely present in nature as...
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