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Article

Predictive modeling of complex ABO glycan phenotypes by lectin microarrays.

Blood advances - 25 Aug 2020

Anani Waseem Q, Ashwood Heather E, Schmidt Anna, Burns Robert T, Denomme Gregory A, Hoffmeister Karin M

Abstract excerpt

Serological classification of individuals as A, B, O, or AB is a mainstay of blood banking. ABO blood groups or ABH antigens, in addition to other surface glycans, act as unique red blood cell (RBC) signatures and direct immune responses. ABO subgroups present as weakened, mixed field, or unexpected reactivity with serological reagents, but specific designations remain complex. Lectins detect glycan motifs with...

Topics

ABO Blood-Group System
Blood Grouping and Crossmatching
Humans
Lectins
Phenotype
Polysaccharides

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32822483
DOI: 10.1182/bloodadvances.2020002051
PMCID: PMC7448608

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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