DNA methylation-based reclassification of olfactory neuroblastoma.

doi:10.1007/s00401-018-1854-7

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

DNA methylation-based reclassification of olfactory neuroblastoma.

Acta neuropathologica - 1 Aug 2018

Capper David, Engel Nils W, Stichel Damian, Lechner Matt, Glöss Stefanie, Schmid Simone, Koelsche Christian, Schrimpf Daniel, Niesen Judith, Wefers Annika K, Jones David T W, Sill Martin, Weigert Oliver, Ligon Keith L, Olar Adriana, Koch Arend, Forster Martin, Moran Sebastian, Tirado Oscar M, Sáinz-Jaspeado Miguel, Mora Jaume, Esteller Manel, Alonso Javier, Del Muro Xavier Garcia, Paulus Werner, Felsberg Jörg, Reifenberger Guido, Glatzel Markus, Frank Stephan, Monoranu Camelia M, Lund Valerie J, von Deimling Andreas, Pfister Stefan, Buslei Rolf, Ribbat-Idel Julika, Perner Sven, Gudziol Volker, Meinhardt Matthias, Schüller Ulrich

Abstract excerpt

Olfactory neuroblastoma/esthesioneuroblastoma (ONB) is an uncommon neuroectodermal neoplasm thought to arise from the olfactory epithelium. Little is known about its molecular pathogenesis. For this study, a retrospective cohort of n = 66 tumor samples with the institutional diagnosis of ONB was analyzed by immunohistochemistry, genome-wide DNA methylation profiling, copy number analysis, and in a subset,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Diagnosis, Differential

Share to DNA Methylation

Share to Isocitrate Dehydrogenase

Share to Neuroblastoma

Share to Olfaction Disorders

Share to Transcriptome

Source

Open in PubMed

Identifiers

PMID: 29730775
DOI: 10.1007/s00401-018-1854-7

Genes

IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA methylation-based reclassification of olfactory neuroblastoma.PMID 29730775Read ↗

Updated Insights into the Molecular Pathophysiology of Olfactory Neuroblastoma Using Multi-Omics AnalysisSemantic proximity Read ↗

IDH2 R172 Mutations Across Poorly Differentiated Sinonasal Tract Malignancies: Forty Molecularly Homogenous and Histologically Variable Cases With Favorable Outcome.Semantic proximity Read ↗

DNA methylation-based classification of sinonasal tumorsSemantic proximity Read ↗

Comprehensive molecular profiling of advanced/metastatic olfactory neuroblastomas.Semantic proximity Read ↗

Recurrent Wnt Pathway and ARID1A Alterations in Sinonasal Olfactory Carcinoma.Semantic proximity Read ↗

Genetic profiling of poorly differentiated sinonasal tumours.Semantic proximity Read ↗

Genomic profiling and immune landscape of olfactory neuroblastoma in ChinaSemantic proximity Read ↗

Genetic and molecular alterations in olfactory neuroblastoma: implications for pathogenesis, prognosis and treatmentSemantic proximity Read ↗

[Genomic profiles and immune microenvironment of olfactory neuroblastoma].Semantic proximity Read ↗

Deconstructing olfactory epithelium developmental pathways in esthesioneuroblastomaSemantic proximity Read ↗

Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory NeuroblastomaSemantic proximity Read ↗

Epigenetic profiling of biphenotypic sinonasal sarcoma across fusion variants and high-grade transformation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.