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Article

Conformational evolution of polymorphic amyloid assemblies.

Current opinion in structural biology - 1 Aug 2018

Liang Chen, Hsieh Ming-Chien, Li Noel X, Lynn David G

Abstract excerpt

The morphological diversity of amyloid assemblies has complicated the development of disease therapies and the design of novel biomaterials for decades. Here we review the conformational evolution of amyloids from the initial liquid-liquid phase separation into the oligomeric particle phase to the nucleation of the more ordered assembly phases. With mounting evidence that the assemblies emerging from the...

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Identifiers

PMID: 29729574
DOI: 10.1016/j.sbi.2018.04.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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