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Identification of four differentially methylated genes as prognostic signatures for stage I lung adenocarcinoma

19 Apr 2018

Abstract excerpt

BACKGROUND: Lung adenocarcinoma (LUAD) is the main subtype of non-small cell lung cancer with a low survival prognosis. We aimed to generate a prognostic model for the postoperative recurrence of LUAD. METHODS: The methylated DNA data of LUAD patients were downloaded from the Cancer Genome Atlas (TCGA). The differentially methylated genes were identified and protein-protein interacting network was constructed,...

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PMID: 29713243
DOI: 10.1186/s12935-018-0547-6

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