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Article

Hepatic fibrosis: It is time to go with hepatic stellate cell-specific therapeutic targets.

Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Jun 2018

Ezhilarasan Devaraj, Sokal Etienne, Najimi Mustapha

Abstract excerpt

Hepatic fibrosis is a pathological lesion, characterized by the progressive accumulation of extracellular matrix (ECM) in the perisinusoidal space and it is a major problem in chronic liver diseases. Phenotypic activation of hepatic stellate cells (HSC) plays a central role in the progression of hepatic fibrosis. Retardation of proliferation and clearance of activated HSCs from the injured liver is an appropriate...

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Identifiers

PMID: 29709350
DOI: 10.1016/j.hbpd.2018.04.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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