Article
Gender specificity improves the early-stage detection of clear cell renal cell carcinoma based on methylomic biomarkers.
Biomarkers in medicine - 1 Jun 2018
Ren Yanjiao, Feng Xin, Xia Xin, Zhang Yexian, Zhang Wenniu, Su Jing, Wang Zhongyu, Xu Ying, Zhou Fengfeng
Abstract excerpt
AIM: The two genders are different ranging from the molecular to the phenotypic levels. But most studies did not use this important information. We hypothesize that the integration of gender information may improve the overall prediction accuracy. MATERIALS & METHODS: A comprehensive comparative study was carried out to test the hypothesis. The classification of the stages I + II versus III + IV of the clear cell...
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