Article
Liver Proteome of Mice with Distinct Genetic Susceptibilities to Fluorosis Treated with Different Concentrations of F in the Drinking Water.
Biological trace element research - 1 Jan 2019
Khan Zohaib Nisar, Sabino Isabela Tomazini, de Souza Melo Carina Guimarães, Martini Tatiana, da Silva Pereira Heloísa Aparecida Barbosa, Buzalaf Marília Afonso Rabelo
Abstract excerpt
Appropriate doses of fluoride (F) have therapeutic action against dental caries, but higher levels can cause disturbances in soft and mineralized tissues. Interestingly, the susceptibility to the toxic effects of F is genetically determined. This study evaluated the effects of F on the liver proteome of mice susceptible (A/J) or resistant (129P3/J) to the effects of F. Weanling male A/J (n = 12) and 129P3/J...
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