Article
Influence of genetic background on fluoride metabolism in mice.
Journal of dental research - 1 Nov 2009
Carvalho J G, Leite A L, Yan D, Everett E T, Whitford G M, Buzalaf M A R
Abstract excerpt
A/J and 129P3/J mouse strains have different susceptibilities to dental fluorosis, due to their genetic backgrounds. This study tested whether these differences are due to variations in water intake and/or F metabolism. A/J (susceptible to dental fluorosis) and 129P3/J mice (resistant) received drinking water containing 0, 10, or 50 ppm F. Weekly F intake, excretion and retention, and terminal plasma and femur F...
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