Article
Inbreeding estimates in human populations: Applying new approaches to an admixed Brazilian isolate.
PloS one - 1 Jan 2018
Lemes Renan B, Nunes Kelly, Carnavalli Juliana E P, Kimura Lilian, Mingroni-Netto Regina C, Meyer Diogo, Otto Paulo A
Abstract excerpt
The analysis of genomic data (~400,000 autosomal SNPs) enabled the reliable estimation of inbreeding levels in a sample of 541 individuals sampled from a highly admixed Brazilian population isolate (an African-derived quilombo in the State of São Paulo). To achieve this, different methods were applied to the joint information of two sets of markers (one complete and another excluding loci in patent linkage...
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