Article
The Impact of FSHR Gene Polymorphisms Ala307Thr and Asn680Ser in the Endometriosis Development.
DNA and cell biology - 1 Jun 2018
André Gustavo Mendonça, Martins Trevisan Camila, Pedruzzi Isabela Nacione, Fernandes Ramon Felix Martins, Oliveira Renato, Christofolini Denise Maria, Bianco Bianca, Barbosa Caio Parente
Abstract excerpt
Endometriosis is an estrogen-dependent inflammatory disease that affects a large number of women in reproductive age. Follicle-stimulating hormone (FSH) plays a role in steroidogenesis and acts through a transmembrane glycoprotein, FSH receptor (FSHR). Polymorphisms in FSHR gene were previously associated with variability in FSH serum level and reproductive outcomes, but its relation with endometriosis has not...
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