Article
Functional analyses of endometriosis-related polymorphisms in the estrogen synthesis and metabolism-related genes.
PloS one - 1 Jan 2012
Wang Hsin-Shih, Wu Hsien-Ming, Cheng Bi-Hwa, Yen Chih-Feng, Chang Pi-Yueh, Chao Angel, Lee Yun-Shien, Huang Hsien-Da, Wang Tzu-Hao
Abstract excerpt
Endometriosis is determined by genetic factors, and the prevalence of genetic polymorphisms varies greatly depending on the ethnic group studied. The objective of this study was to investigate the relationship between single nucleotide polymorphisms (SNPs) of 9 genes involved in estrogen biosynthesis and metabolism and the risks of endometriosis. Three hundred patients with endometriosis and 337 non-endometriotic...
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