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Article

NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program.

Stem cell reports - 5 Jun 2018

FitzPatrick Lorna M, Hawkins Kate E, Delhove Juliette M K M, Fernandez Emilio, Soldati Chiara, Bullen Louise F, Nohturfft Axel, Waddington Simon N, Medina Diego L, Bolaños Juan P, McKay Tristan R

Abstract excerpt

Human neural development begins at embryonic day 19 and marks the beginning of organogenesis. Neural stem cells in the neural tube undergo profound functional, morphological, and metabolic changes during neural specification, coordinated by a combination of exogenous and endogenous cues. The temporal cell signaling activities that mediate this process, during development and in the postnatal brain, are...

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Identifiers

PMID: 29681545
DOI: 10.1016/j.stemcr.2018.03.015
PMCID: PMC5989595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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