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Article

Cardiac manifestations in sickle cell disease varies with patient genotype.

British journal of haematology - 1 Jun 2018

Guedeney Paul, Lionnet François, Ceccaldi Alexandre, Stankovic Stojanovic Katia, Cohen Ariel, Mattioni Sarah, Montalescot Gilles, Bachmeyer Claude, Isnard Richard, Haymann Jean-Philippe, Hammoudi Nadjib

Abstract excerpt

Cardiac involvement is well characterized in sickle cell anaemia (SCA) but cardiac features associated with Haemoglobin SC (HbSC) disease are mostly unknown. We compared 60 patients with HbSC disease (median age 31 years, 25 men) to 60 SCA patients and 60 controls matched for age and gender. Left ventricular ejection fraction (LVEF), left ventricle (LV) mass index (LVMi), cardiac index and peak tricuspid...

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Identifiers

PMID: 29676452
DOI: 10.1111/bjh.15238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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