Cardiac complications in thalassemia throughout the lifespan: Victories and challenges

Abstract excerpt

Thalassemias are among the most common hereditary diseases in the world because heterozygosity offers protection against malarial infection. Affected individuals have variable expression of alpha or beta chains that lead to their unbalanced utilization during hemoglobin formation, oxidative stress, and apoptosis of red cell precursors prior to maturation. Some individuals produce sufficient hemoglobin to survive...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Erythropoietin and Anemia Treatment
• Share to Hemoglobinopathies and Related Disorders
• Share to Iron Metabolism and Disorders