Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of SYN1Q555X mutation on cortical gray matter microstructure.

Human brain mapping - 1 Aug 2018

Cabana Jean-François, Gilbert Guillaume, Létourneau-Guillon Laurent, Safi Dima, Rouleau Isabelle, Cossette Patrick, Nguyen Dang Khoa

Abstract excerpt

A new Q555X mutation on the SYN1 gene was recently found in several members of a family segregating dyslexia, epilepsy, and autism spectrum disorder. To describe the effects of this mutation on cortical gray matter microstructure, we performed a surface-based group study using novel diffusion and quantitative multiparametric imaging on 13 SYN1Q555X mutation carriers and 13 age- and sex-matched controls....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Cell Cycle Proteins
Share to Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gray Matter

Share to Magnetic Resonance Imaging

Share to Multimodal Imaging

Share to Pedigree

Share to Synapsins

Source

Open in PubMed Open full text

Identifiers

PMID: 29671924
DOI: 10.1002/hbm.24186
PMCID: PMC6866302

Genes

SYN1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of SYN1Q555X mutation on cortical gray matter microstructure.PMID 29671924Read ↗

Large-scale structural alteration of brain in epileptic children with SCN1A mutation.Semantic proximity Read ↗

A Neuregulin-1 schizophrenia susceptibility variant causes perihippocampal fiber tract anomalies in healthy young subjects.Semantic proximity Read ↗

Reduced Brain Volume and White Matter Alterations in Shank3-Deficient RatsSemantic proximity Read ↗

SYT1 Gene-Wide Analysis on White Matter Microstructure in Adulthood ADHDSemantic proximity Read ↗

Frontal deficits and atrophy in a patient with neuroserpinosis detected by single-case voxel-based morphometry: A case reportSemantic proximity Read ↗

Anatomic & metabolic brain markers of the m.3243A>G mutation: A multi-parametric 7T MRI study.Semantic proximity Read ↗

PLP1 and CNTN1 gene variation modulates the microstructure of human white matter in the corpus callosum.Semantic proximity Read ↗

Elucidating microstructural alterations in neurodevelopmental disorders: application of advanced diffusion-weighted imaging in children with RasopathiesSemantic proximity Read ↗

Diffusion tensor imaging of patients with proteolipid protein 1 gene mutations.Semantic proximity Read ↗

Individual fixel-based white matter abnormalities in the epilepsiesSemantic proximity Read ↗

Elucidating Microstructural Alterations in Neurodevelopmental Disorders: Application of Advanced Diffusion‐Weighted Imaging in Children With RasopathiesSemantic proximity Read ↗

DISC1 is associated with cortical thickness and neural efficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.