Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced lymphotoxin-beta production by tumour cells is associated with loss of follicular dendritic cell phenotype and diffuse growth in follicular lymphoma.

The journal of pathology. Clinical research - 1 Apr 2018

Pepe Giuseppina, Di Napoli Arianna, Cippitelli Claudia, Scarpino Stefania, Pilozzi Emanuela, Ruco Luigi

Abstract excerpt

Cytokine production is essential for follicular dendritic cell (FDC) maintenance and organization of germinal centres. In follicular lymphoma, FDCs are often disarrayed and may lack antigens indicative of terminal differentiation. We investigated the in situ distribution of cells producing lymphotoxin-beta (LTB), lymphotoxin-alpha (LTA), and tumour necrosis factor-alpha (TNFA) transcripts in human reactive lymph...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Germinal Center

Share to Immunohistochemistry

Share to In Situ Hybridization

Share to Lymph Nodes

Share to Lymphoma, Follicular

Share to Lymphotoxin-alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 29665320
DOI: 10.1002/cjp2.97
PMCID: PMC5903694

Genes

LTB
LTA
CXCL13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Reduced lymphotoxin-beta production by tumour cells is associated with loss of follicular dendritic cell phenotype and diffuse growth in follicular lymphoma.PMID 29665320Read ↗

Lymphotoxin-β Receptor-Dependent Genes in Lymph Node and Follicular Dendritic Cell TranscriptomesSemantic proximity Read ↗

Follicular dendritic cells: origin, phenotype, and function in health and disease.Semantic proximity Read ↗

Establishment of lymphotoxin beta receptor signaling-dependent cell lines with follicular dendritic cell phenotypes from mouse lymph nodes.Semantic proximity Read ↗

Peripheral T-cell lymphoma with follicular involvement and a CD4+/bcl-6+ phenotype.Semantic proximity Read ↗

Dendritic cells are significantly reduced in non-Hodgkin's lymphoma and express less CCR7 and CD62L.Semantic proximity Read ↗

Antigenic phenotyping of human follicular dendritic cells isolated from nonmalignant and malignant lymphatic tissue.Semantic proximity Read ↗

The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissues.Semantic proximity Read ↗

In situ localization of follicular lymphoma: description and analysis by laser capture microdissectionSemantic proximity Read ↗

Follicular Colonization in B-Cell Lymphoma of Mucosa-Associated Lymphoid TissueSemantic proximity Read ↗

Usefulness of follicular dendritic cell pattern in classification of peripheral T-cell lymphomas.Semantic proximity Read ↗

Expression of the lymphotoxin β receptor on follicular stromal cells in human lymphoid tissuesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.