Article
High-grade PanIN presenting with localised stricture of the main pancreatic duct: A clinicopathological and molecular study of 10 cases suggests a clue for the early detection of pancreatic cancer.
Histopathology - 1 Aug 2018
Yokode Masataka, Akita Masayuki, Fujikura Kohei, Kim Mi-Ju, Morinaga Yukiko, Yoshikawa Seiichi, Terada Takuro, Matsukiyo Hiroshi, Tajiri Takuma, Abe-Suzuki Shiho, Itoh Tomoo, Hong Seung-Mo, Zen Yoh
Abstract excerpt
AIMS: This study aimed to identify the pathological features of high-grade PanIN that presents with imaging-detectable abnormalities. METHODS AND RESULTS: Ten cases of isolated, main-duct, high-grade PanIN as the primary clinical presentation were identified. All patients presented with stenosis of the main pancreatic duct, with two being associated with extensive upstream duct dilatation (>5 mm in diameter)....
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