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Article

Toward a porcine in vivo model to analyze the pathogenesis of TLR5-dependent enteropathies.

Gut microbes - 9 Nov 2020

Pieper Robert, van Best Niels, van Vorst Kira, Ebner Friederike, Reissmann Monika, Hornef Mathias W, Fulde Marcus

Abstract excerpt

Non-communicable diseases, such as the metabolic syndrome and inflammatory bowel disease, constitute serious public health threats in developed countries. Besides environmental factors, genetic predispositions contribute to the onset and progression of the disease. State-of-the-art mouse models recently highlight the involvement of Toll-like receptor 5 (TLR5)-driven microbiota composition in the development of...

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Identifiers

PMID: 32715918
DOI: 10.1080/19490976.2020.1782163
PMCID: PMC7524303

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